BDBM50017674 (2-Benzhydryloxy-ethyl)-dimethyl-amine::2-(benzhydryloxy)-N,N-dimethylethanamine::2-(diphenylmethoxy)-N,N-dimethylethanamine::Antitussive::Beldin::Belix::Benadryl::Benylin::CHEMBL657::DIMENHYDRINATE::DIPHENHYDRAMINE::Dibenil::Diphen::Hydramine::N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE::Silphen::US9138431, DIPHENHYDRAMINE (Benadryl)::US9333199, DIPHENHYDRAMINE (Benadryl)

SMILES CN(C)CCOC(c1ccccc1)c1ccccc1

InChI Key InChIKey=ZZVUWRFHKOJYTH-UHFFFAOYSA-N

Data  20 KI  22 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017674   

TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50017674((2-Benzhydryloxy-ethyl)-dimethyl-amine | 2-(benzhy...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50017674((2-Benzhydryloxy-ethyl)-dimethyl-amine | 2-(benzhy...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50017674((2-Benzhydryloxy-ethyl)-dimethyl-amine | 2-(benzhy...)
Affinity DataIC50: >1.35E+5nMAssay Description:Binding affinity towards nicotinic acetylcholine receptor (nACh) using [3H](-)-nicotine as radioligand in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed